hrp0084p3-639 | Bone | ESPE2015

Is Serum Serotonin Involved in the Bone Loss of Young Females with Anorexia Nervosa?

Maimoun Laurent , Guillaume Sebastien , Lefebvre Patrick , Philibert Pascal , Bertet Helena , Picot Marie-Christine , Gaspari Laura , Paris Francoise , Mariano-Goulart Denis , Renard Eric , Sultan Charles

Objective: Recent experimental data suggest that circulating serotonin interacts with bone metabolism, although this is less clear in humans. This study investigated whether serum serotonin interferes with bone metabolism in young women with anorexia nervosa (AN), a clinical model of energy deprivation.Methods: Serum serotonin, markers of bone turnover (osteocalcin (OC), procollagen type 1 N-terminal propeptide (PINP), type 1-C telopeptide breakdown prod...